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Preparative HPLC System Pilot 200

    Publish time 2026-06-27 11:03    
Preparative HPLC System Pilot 200

     The Pilot Series Preparative Liquid Chromatography System is a highly efficient, powerful, and modular preparative LC system. It improves the separation and purification processes for herbal medicines, synthetic chemical drugs, and biomacromolecules. The system supports gradient elution with up to five different mobile phases, simultaneous dual-wavelength online detection, and comes with software that complies with CFDA GxP and FDA 21 CFR Part 11 regulatory requirements. It features an audit trail function, allows easy method storage and recall, and enables fraction collection to be performed on the same platform. The system is suitable for applications ranging from laboratory research to industrial-scale production.

 

Feature

 Quickly purifies and prepares active compounds from both small molecules and biomacromolecules

Modular design with built-in fraction collection for easy system expansion and upgrades

Cam curve compensation reduces flow pulsation and keeps baseline noise low

Multi-point flow calibration ensures accurate and reproducible flow across the full range

Pump head auto-wash prevents buffer salt residue and crystallization

Dual-wavelength detection (190–800 nm) for online analysis

Easy lamp and flow cell replacement; deuterium and tungsten lamps switch automatically

Supports optional detectors: UV-VIS, ELSD, RI, and more

Optimized mixer path ensures efficient mixing with minimal dead volume

Flow path materials available: 316L stainless steel, PEEK, titanium, and Hastelloy

Automated fraction collector with multiple collection modes and tube size options

Software compliant with CFDA GXP and FDA 21 CFR Part 11

Database-based project management; all methods and data stored under each project

Full audit trail and user permission management.

 

Technical Specifications:

Model  

Pilot   200

HPLC   Pump

High-precision   316L pump, optional: PEEK, titanium, Hastelloy

Flow   Range

0.01~200 mL/min

Flow   Accuracy

≤ ±0.5%

Flow   Reproducibility

≤ 0.1%

Pressure   Range

0~10 MPa

Pulsation

≤   0.1 MPa

Elution   Mode

Isocratic,   linear & step gradient; freely combinable and customizable

Elution   Mode

Isocratic,   linear & step gradient; freely combinable and customizable

Detector   Lamp

Deuterium   and tungsten lamps, with automatic light source switching

Wavelength

190~800   nm, dual-wavelength online detection

Wavelength   Accuracy

±1 nm

Wavelength   Precision

≤  0.1 nm

Absorbance   Range

0~3 AU

Baseline   Noise

≤   ±0.5x10-5 AU

Baseline   Drift

≤   1.5x10-4 AU/h

Collection   Method

Automated   fraction collector

Collection   Rack

120-position   15 mL glass test tubes/42-position 50 mL centrifuge tubes

Collection   Mode

Manual,   full, range, peak-based (time/threshold/slope)

Injection   Method

Manual   injection valve (various loop sizes), solid loading, and pump loading

Software

PC   software workstation (Windows) via USB or RS232

Fully   compliant with CFDA GxP and FDA 21 CFR Part 11

Power   Supply

100~240   VAC, 50/60 Hz

Dimension

Pump:   370x240x152mm UV detector: 370x240x152mm Collector: 355x241x320mm